David is a (medicinal) synthetic chemist. He undertook his Master’s Degree in Chemistry at The University of York, UK, spending his final year at Takeda Pharmaceuticals in Cambridge, UK. In 2016, he embarked on a PhD in Fragment-based Drug Discovery, designing 3D cyclobutane fragments, within the group of Prof. Iwan de Esch at the Vrije Universiteit Amsterdam. David joined Incircular in 2022.

George is a biochemist, completing his PhD in 2021 specialized in de novo heme-protein design at the University of Bristol, UK. George then joined the Grossmann group at VU Amsterdam as a postdoc, helping to develop the INCYPRO technology through a combination of experimental and computational techniques, prior to joining the Incircular team at the start of 2024.

Lorenzo is a biologist. He received his Master’s degree in Molecular Biology and Genetics from the University of Pavia, Italy. Lorenzo started his career at the Department of Molecular Medicine Pavia where his work involved cloning, protein expression, purification and characterization. In 2021, Lorenzo joined the Incircular team

Marcelo is a chemist with a specialization in computational molecular modeling and bioinformatics. He received his PhD from the University of Groningen in 2010. After several post-doctoral research projects, he became a senior researcher at the University of Amsterdam (Prof. Mutti). Marcelo is also a chemistry teacher. Marcelo has been part of the Incircular team since 2022.

Saskia is a chemist. After her chemistry studies at the Free University Berlin, she continued with her PhD in chemical biology at the Humboldt University in Berlin. She then became associate editor for chemistry journals at Wiley-VCH. In 2016, Saskia joined Tom’s group as project leader at the VU University Amsterdam and continued research on INCYPRO. She launched Incircular in 2021.

Sharmila is a biochemist. She holds a Master’s degree in Biomedical Sciences from the University of Glasgow. She started her career in bacterial protein expression and purification at the Translational Research Platform for Veterinary Biologicals, India. Sharmila is part of the Incircular team since 2022.